Restasis (Cyclosporine)

Name: Restasis
Brand: Allergan
SKU: 6493
Availability: InStock

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Restasis 30 x 0.4ml Vials (EXPIRY 02/26)

Manufacturer: Allergan

Country: United States

Dosage: 0.05 %

Qty-Price (USD):

Type:

Product: Restasis 30 x 0.4ml Vials

Manufacturer: Abbvie

Country: Canada

Dosage: 0.05 %

Qty-Price (USD):

Type:

Product: Restasis 60 x 0.4ml Vials

Manufacturer: Abbvie

Country: Canada

Dosage: 0.05 %

Qty-Price (USD):

Generic Equivalent of Restasis

Type

Product

Manufacturer

Country

Dosage

Qty-Price (USD)

Type:

Product: Cyclosporine 30 x 0.4ml Vials

Manufacturer: Generic

Country: Canada

Dosage: 0.05 %

Qty-Price (USD):

Type:

Product: Cyclosporine Eye Drops (ON BACKORDER)

Manufacturer: Generic

Country: India

Dosage: 0.05 %/3 ml

Qty-Price (USD):

Type:

Product: Cyclosporine 3ml (Cyclomune - Sun Pharma)

Manufacturer: Generic

Country: India

Dosage: 0.1 %

Qty-Price (USD):

Restasis Information

medically reviewed by Carol Hou (BSc. Pharm) on August 29, 2025.

A licensed pharmacist (Licensed Community Pharmacies Directory | College of Pharmacists of British Columbia) with over 20 years of experience in medication management, specifically medication safety, she has reviewed the information for accuracy and completeness.

Restasis and Cyclosporine Ophthalmic Emulsion at CanadaPharmacyOnline.com

The brand-name Restasis (cyclosporine ophthalmic emulsion) is available in many countries worldwide, including India, and is manufactured by Allergan. In Canada, it is distributed by AbbVie Corporation (AbbVie acquired Allergan, the original developer of Restasis).

Generic cyclosporine ophthalmic emulsion is sourced from manufacturers that meet applicable regulatory standards. The specific manufacturer of your dispensed medication may vary.

Important Information about Generic Cyclosporine Ophthalmic Emulsion:

Generic cyclosporine ophthalmic emulsion contains the same active ingredient as brand-name Restasis and is required to meet the same safety, effectiveness, and quality standards. This means it is designed to work in the same way as Restasis. Studies have demonstrated bioequivalence between generic and brand-name cyclosporine ophthalmic emulsion, meaning they have comparable absorption rates and overall effects. This ensures that generic versions meet the same safety, effectiveness, and quality standards as the brand-name medication. Talk to your doctor or pharmacist if you have any questions about using generic cyclosporine ophthalmic emulsion.

For more information about generic drug approval and bioequivalence, you can visit the FDA website: https://www.fda.gov/drugs/generic-drugs/generic-drug-facts.

Dosage:

Brand Restasis is available in a concentration of 0.05% in 0.4 ml single-use vials. Generic cyclosporine ophthalmic emulsion is also available in a 0.05% concentration, typically in 0.4 mL single-use vials; however, some generic formulations may also be available in multi-dose bottles (e.g., 3 mL, as offered by this pharmacy).

Your doctor will determine the appropriate dose based on your individual needs and medical conditions.

Usage:

Restasis (cyclosporine ophthalmic emulsion) is an eye drop medication primarily prescribed to increase natural tear production in individuals experiencing chronic dry eye disease, particularly when reduced tear production is linked to inflammation. Its active ingredient, cyclosporine, works by suppressing inflammation in the tear glands and eyes, which in turn helps restore the eyes' ability to produce their tears. It's crucial to understand that Restasis isn't a quick fix; it targets the underlying cause of dry eye and typically requires consistent, long-term use (often several months) for patients to experience significant improvement in tear production and a reduction in symptoms, such as burning, stinging, and gritty sensations.

Mechanism of Action:
Restasis (cyclosporine ophthalmic emulsion) works by addressing the underlying inflammation often responsible for chronic dry eye. Its primary mechanism is immunomodulation through the inhibition of calcineurin, an enzyme essential for the activation of T-cells. By blocking calcineurin, Restasis reduces the proliferation of these inflammatory T-cells and decreases the production of pro-inflammatory cytokines on the ocular surface. This reduction in inflammation enables the tear glands to resume their more normal function, resulting in increased natural tear production over time.

Use Restasis exactly as your doctor prescribes, following the instructions in the product monograph in Canada. Consult your doctor for personalized guidance and safe use.

The information below summarizes some, but not all, potential side effects, risks, and interactions. Before using Restasis, it is essential to discuss all possible side effects, risks, and interactions with your doctor or pharmacist.

Side Effects:

The information below outlines potential side effects associated with Restasis (cyclosporine ophthalmic emulsion). It is not an exhaustive list, and individual reactions can vary.

Common Side Effects - The following are some common side effects of Restasis; however, other side effects may occur. Contact your doctor promptly if any side effects are persistent, worsening, or concerning, or if you experience any other concerning symptoms.
• Blurred vision
• Eye pain, discharge, or redness
• Foreign body sensation: A feeling that something is in the eye.
• Itching eyes
• Temporary burning or stinging: This is the most common side effect and often occurs right after instilling the drops. It typically subsides quickly. Chilling the drops in the refrigerator for a few minutes before use may help lessen this sensation.

Serious Side Effects: These are rare but potentially severe side effects. Seek immediate medical attention or call emergency services if you experience any of the following:
• Persistent or Worsening Vision Changes: While temporary blurred vision is a common side effect, any vision changes that persist or worsen should be evaluated by a healthcare professional.
• Signs of an Allergic Reaction: While rare, a severe allergic reaction can occur. Symptoms may include hives, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing.
• Signs of an Eye Infection: This can occur if the eye drop container becomes contaminated. Symptoms may include increased redness, discharge, severe discomfort, or swollen eyelids.

Contraindications:

The following is not an exhaustive list of contraindications. Before starting Restasis, it is crucial to discuss all your medical conditions, past and present, and all medications you are taking with your doctor or pharmacist.

Restasis should not be used in the following circumstances:
• Active Ocular (Eye) Infection: Restasis is contraindicated in patients with an active eye infection. Its immunosuppressive properties could potentially worsen the infection
• Known Hypersensitivity: If you have a known or suspected hypersensitivity or allergy to cyclosporine or any of the ingredients in the formulation. An allergic reaction can range from mild symptoms, such as a rash, to severe, life-threatening reactions.

Tell your doctor about all of your medical conditions, past and present, before starting Restasis. This is crucial because certain conditions can affect whether Restasis is right for you. These conditions may include, but are not limited to:
• History of Herpes Keratitis: The safety and efficacy of Restasis have not been studied in patients with a history of herpes keratitis. The medication should be used with caution in these patients.
• Severe Dry Eye: The effectiveness of Restasis as a standalone treatment has not been demonstrated in patients with very severe dry eye (DEWS Classification Level 4). It is typically used for moderate cases, and more aggressive treatments may be needed.
• Specific Dry Eye Conditions: Restasis has not been studied in patients whose dry eye is caused by end-stage lacrimal gland disease or Vitamin A deficiency/scarring. Therefore, its effectiveness for these specific conditions is not known.

Drug Interactions:

Before taking Restasis, it is essential to discuss all potential risks and interactions with your doctor or pharmacist. For complete and up-to-date information, please visit the official product monograph at: https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/RESTASIS_PM_EN.pdf.

Provide your doctor with a complete list of all your medications, including prescriptions, over-the-counter (OTC) drugs, vitamins, and herbal supplements. It is also important to inform your doctor about any herbal teas or significant dietary changes you are making, as these could potentially interact with the medication.
• Contact Lenses: Restasis should not be administered while wearing contact lenses. Contact lenses should be removed before using the eye drops, and you should wait at least 15 minutes before reinserting them. The lens material may absorb the excipients of the medication.
• Other Eye Drops: Do not administer Restasis at the same time as other eye drops. To avoid washing out the medication, you should wait at least 15 minutes after using Restasis before applying any other eye drops, such as artificial tears.
• Punctal Plugs & Anti-inflammatory Agents: Some studies have found that the effectiveness of Restasis at improving tear production may be reduced when used concurrently with anti-inflammatory eye drops or punctal plugs.

Pregnancy and Breastfeeding

The use of Restasis during pregnancy requires careful consideration. There are no adequate and well-controlled studies of the drug in pregnant women. While animal studies have shown reproductive toxicity at high oral doses, the systemic absorption from ophthalmic administration is minimal. Restasis should only be used during pregnancy if the potential benefits to the mother outweigh the potential risks to the fetus.

It is not known if cyclosporine is excreted in human milk after being administered as an eye drop. Although systemic blood concentrations are often undetectable, caution should be exercised when Restasis is administered to a nursing woman.

Use in Children

The safety and efficacy of Restasis have not been established in pediatric patients. Therefore, the medication is not recommended for use in children.

Frequently Asked Questions about Restasis at Canada Pharmacy Online:

Why is Restasis more affordable in Canada than in the United States?

Prescription drug prices, including Restasis, are generally lower in Canada than in the US due to a combination of factors, primarily government price regulations, differing market dynamics, and other economic considerations. In Canada, provincial and federal governments negotiate drug prices with pharmaceutical companies, which often results in lower costs compared to the U.S., where market forces play a more significant role. For more information, see the FAQs on Prescription Drug Importation from the Kaiser Family Foundation (KFF): https://www.kff.org/health-costs/issue-brief/faqs-on-prescription-drug-importation/

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy is dedicated to providing you with the lowest prices on high-quality products.

How do I place an order with your pharmacy?

Ordering from us is very simple. You can purchase online or call Customer Service at 1866.920.3784 for more information or to learn about the ordering process. Visit our How to Order page.

Is there a limit on the number of Restasis I can order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three-month supply of Restasis at a time, as per your doctor's prescription.

Can I buy over the counter from you?

No, Restasis requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes 7 to 18 business days to receive your order from our pharmacy.

Is there a generic for Restasis?

Yes, there is a generic alternative for this product called cyclosporine ophthalmic emulsion.

Can I stop using Restasis once my dry eye symptoms improve?

No, it is not recommended to stop using Restasis once your symptoms improve. Dry eye disease is often a chronic condition that requires long-term management and treatment. Restasis (cyclosporine ophthalmic emulsion) works by increasing your eyes' natural ability to produce tears, and it can take several months for the full effect to be achieved. Discontinuing the medication may cause your dry eye symptoms to return gradually.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions.

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