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The Bone Condition That Surprisingly Increases Your Risk of Mortality


written by Dr. Christine Bishara - Feb 17, 2025

Photo Credit: by Tima Miroshnichenko, Pexels.com
Photo Credit: by Tima Miroshnichenko, Pexels.com

Strong bones are the foundation of a healthy, active life. Unfortunately, bone conditions such as osteopenia and osteoporosis often develop unnoticed until it's too late. Did you know that nearly 60% of postmenopausal women experience osteopenia (a decreased density of bones) or osteoporosis (a more severe decrease in bone density) that makes bones more prone to fractures?

These conditions are not just women’s issues—they increasingly affect aging men, too. Osteopenia and osteoporosis heighten fracture risks, posing serious personal and public health challenges. The good news? The power to build stronger bones is in your hands. Simple lifestyle changes, early detection, and preventive measures can make an impact. Prevalence of osteoporosis in postmenopausal women

Osteopenia and Osteoporosis in Postmenopausal Women

Menopause: a time of change, reflection, and surprisingly, a major turning point for women’s bones. As estrogen levels dip, so does your bone density, quietly raising the risk of osteopenia and osteoporosis. These conditions can sneak up on you, weakening your bones until a fall leads to a fracture. Understanding the link between menopause and bone health is the first step toward protecting yourself.

A Few Things You Need to Know:

Impact of Hormonal Changes

The drop in estrogen levels during menopause is a key factor in the progressive loss of bone density in postmenopausal women. Estrogen is crucial for maintaining bone mass by regulating the balance between bone formation and bone resorption (maintenance and absorption of bone minerals released into the bloodstream). As estrogen levels drop, this balance is disrupted, leading to accelerated bone loss. This hormonal shift can result in a rapid decrease in bone mineral density, often progressing from osteopenia to osteoporosis if left unaddressed.

Increased Risk of Fractures

The combination of reduced bone density and structural changes in bone tissue significantly elevates the risk of fractures in postmenopausal women. This increased fragility makes even minor falls or impacts potentially dangerous, with hip, spine, and wrist fractures being the most common. Studies have shown that postmenopausal women with osteoporosis have a 40% lifetime risk of experiencing at least one osteoporotic fracture, highlighting the urgent need for preventive strategies and early intervention. Prevention and treatment of postmenopausal osteoporosis

Further complicating this are the statistics that show a high mortality rate of certain fractures, such as hip fractures, in those over 65. Mortality in those over 65 after hip fractures

Osteopenia and Osteoporosis in Men and Andropause

As men age, testosterone levels naturally decline—a process known as andropause. This gradual decrease impacts bone health by reducing bone mineral density (BMD) and increasing bone resorption, which raises the risk of osteopenia and osteoporosis. While these conditions are more common in women, men should also be mindful of their bone health as they age, as the risk, though less frequent, is still significant. Testosterone plays a crucial role in maintaining bone strength by stimulating osteoblast activity and slowing bone turnover. Research shows that testosterone replacement therapy can effectively improve bone mineral density in men with low testosterone, providing a promising option to combat age-related bone loss.

Testosterone and bone health

Lower Awareness but Significant Fracture Risks

Despite the growing recognition of osteoporosis in men, awareness remains significantly lower compared to women. Men typically experience fractures about 10 years later than women due to their higher peak bone mass, but the consequences are often more severe. Hip fractures, for example, carry a higher risk of morbidity and mortality in men. Approximately 13–30% of men over 50 will experience an osteoporosis-related fracture in their lifetime, underscoring the need for better diagnosis and preventive care.

Gender differences in osteoporosis

Lifestyle Modifications for Improved Bone Health:

1-Early Detection

Early detection is key. Think of early detection as your first step in keeping your bones strong and healthy. Getting screened helps you and your doctor spot any potential issues early on, so you can take action before they lead to problems like fractures. It’s all about being proactive and taking charge of your bone health. The U.S. Preventive Services Task Force (USPSTF) recommends routine bone density screening for women aged 65 and older and for postmenopausal women under 65 with specific risk factors, such as a family history of fractures, low body weight, or smoking.

Osteoporosis and prevention of factors

Proactively addressing osteopenia and osteoporosis through early diagnosis and treatment is a powerful step toward safeguarding your bone health and overall quality of life. These conditions develop quietly, but with regular screenings and timely intervention, you can stay ahead of potential complications. This is especially important for individuals at higher risk due to factors like age or hormonal changes. By working closely with healthcare providers, you can create a personalized care plan that includes effective medications, lifestyle adjustments, and tailored nutritional strategies.

2-Balanced Diet Rich in Calcium and Vitamin D

To keep your bones healthy, a well-balanced diet is crucial for maintaining their integrity. Foods rich in calcium, such as dairy products, leafy greens, nuts, and fortified foods, help build and preserve bone density. Vitamin D, obtained from fatty fish, eggs, fortified foods, or sunlight exposure, enhances calcium absorption and supports bone metabolism.

3-Regular Weight-Bearing Exercises

Engaging in weight-bearing activities like walking, jogging, dancing, or resistance training strengthens bones by stimulating bone formation. These exercises improve bone density and reduce the risk of fractures by targeting vulnerable areas such as the hips, spine, and wrists. To maximize benefits, aim for 30 minutes of weight-bearing exercises at least 4–5 days per week and resistance training 2–3 times per week, performing 2–3 sets of 8–12 repetitions for major muscle groups

Exercise and osteoporosis prevention

4-Avoidance of Smoking and Excessive Alcohol Consumption

Smoking weakens bones by reducing blood supply, slowing the production of bone-forming cells, and decreasing calcium absorption, which can lead to osteoporosis and fractures. Similarly, excessive alcohol consumption disrupts bone metabolism by impairing calcium and vitamin D absorption, altering hormone levels, and increasing bone breakdown. To protect bone health, it is essential to quit smoking and limit alcohol intake.

https://www.healthline.com/health/osteoporosis/osteoporosis-and-alcohol?utm

Treatment Strategies

1-Vitamin D and Calcium Supplements

Calcium and vitamin D are a good start. They are essential for bone health, aiding bone density maintenance and fracture prevention. Vitamin D enhances calcium absorption, while both nutrients reduce the risk of osteoporosis and fractures, particularly in older adults.

Buy Vitamin D Online – Cholecalciferol from Canada

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2-Hormone replacement therapy (HRT) can prevent bone loss in postmenopausal women. The type of hormone replacement does matter. Bioidentical (HRT) is superior to synthetic hormone replacement because it reduces the risk of complications. There are some contraindications, so it is very important to discuss this with your doctor and weigh the benefits with the risks. The majority of women do not have significant contraindications that prevent them from treatment and may benefit from HRT. Topical and patch forms may be safe options for HRT.

3-Bisphosphonates

Bisphosphonates are the primary medications for treating and preventing osteoporosis. They work by slowing bone breakdown, helping to maintain or slightly increase bone density. Common options include alendronate, ibandronate, risedronate, and zoledronic acid. These can be taken as weekly or monthly pills or as annual injections. Raloxifene is another option that helps maintain bone density and may reduce breast cancer risk.

Alendronate/Fosomax

Ibandronate/Boniva

Risedronate/Actonel

Zoledronic Acid/Reclast

Raloxifene/Evista

As always, its important to discuss your risks and options with your doctor so you can both come up with a good treatment strategy. This article is for information purposes only.

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