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Rozlytrek (Entrectinib)

Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
Type: drug type
Product: Rozlytrek Capsule
Manufacturer: Hoffman - La Roche
Country: Canada
Dosage: 200 mg
Qty-Price (USD):

Generic Equivalent of Rozlytrek
Type
Product
Manufacturer
Country
Dosage
Qty-Price (USD)
There is no generic product of Rozlytrek.

Rozlytrek Information

Rozlytrek Details (Brand and Generic)

CanadaPharmacyOnline.com currently offers the brand Rozlytrek from Canada manufactured by Hoffman - La Roche. The generic version is not available. Payment is required before the order is processed and no cancellation is allowed. Our customers may also purchase other cancer medications such as Alecensa and Afinitor.

Dosage

The brand Rozlytrek comes in the strength of 200 mg capsules.

Usage

Rozlytrek (entrectinib) is used to treat solid tumours and lung cancer. Rozlytrek is used to treat adults with solid tumours that have a Neurotrophic Tyrosine Receptor Kinase (NTRK) gene fusion without a known resistance mutation. Rozlytrek can treat cancers that have spread to different parts of the body. It is for patients without other treatment options. To benefit from Rozlytrek, the patient must have a tumour that has an NTRK gene fusion. This can be checked by a test that is done before you start Rozlytrek. Rozlytrek is used to treat adults with a kind of lung cancer called non-small cell lung cancer (NSCLC). The non-small cell lung cancer is “ROS1-positive” (this means that your cancer cells have a fault in a gene called ‘ROS1’), and may have spread to other parts of your body, and has not been treated with another drug called crizotinib. To benefit from Rozlytrek, the patient must have non-small cell lung cancer (NSCLC) that is ROS1-positive. Rozlytrek works by blocking the action of enzymes which have a fault in them. This fault is in the NTRK genes that make the enzymes. The faulty enzymes encourage the cancer cells to grow. Rozlytrek may slow down or stop the cancer from growing. It may also help to shrink your cancer. Continue to take Rozlytrek unless your healthcare provider tells you to stop. Take Rozlytrek with or without food. Swallow whole. Do not open or dissolve the capsules. If you vomit right after taking a dose, you may take the dose again. (entrectinib) is not recommended for use in children less than 18 years of age. There is a higher risk of bone fractures in children compared to adults when using (entrectinib).

Side Effects and Precautions

The common side effects of Rozlytrek may include tiredness; difficulty sleeping; constipation; diarrhea; nausea; vomiting; abdominal pain; change in sense of taste and touch; swelling; dizziness, headaches; abnormal touch sensation (tingling, pain or numbness in hands, fingers and toes); pain in joints, bones, muscles or nerves; weakness of muscles; weight gain; loss of appetite; difficulty swallowing; cough, fever, rash.

Stop using Rozlytrek and call your doctor right away if you have the following serious side effects: anemia (reduction in the number of red blood cells): feeling tired, looking pale and heart pumping; decreased neutrophils (a kind of white blood cells): fever, fatigue, mouth ulcer, sore throat, or infections; dehydration: thirst, reduced sweating and urine, dry mouth, dizziness; eye problems: blurred vision, loss of vision in eye, double vision, increased sensitivity of the eyes to light, clouding of lens in eye, spots in vision that appear as specks or strings of floating material; liver problems and increased liver enzymes: loss of appetite, feeling sick or being sick, yellow skin, itching or pain in your liver area; lung problems/infections: difficult and painful breathing, shortness of breath, sore throat, cough, sinus congestion; nervous System / Cognitive Disorders: feeling confused, mental status change, anxiety, persistent sad mood, decreased attention and awareness; disorientation, agitation; having memory problems; urinary tract infection: blood in urine, pain when you go pee; ataxia (lack of muscle coordination): difficulty with fine motor tasks such as eating, writing or buttoning shirt; difficulty walking; loss of balance; slurring speech; congestive heart failure (heart does not pump blood as well as it should); hypotension (low blood pressure): dizziness, fainting, lightheadedness; hyperuricemia (high levels of uric acid in the blood); prolongation of QT interval (a heart rhythm condition); urinary retention (difficulty emptying bladder). This is not a complete list of side effects. For any unexpected effects while taking Rozlytrek, contact your doctor or pharmacist.

Warnings and Interactions

Avoid becoming pregnant while taking Rozlytrek. It may harm your unborn baby. Use highly effective birth control if you can get pregnant while taking Rozlytrek and for 5 weeks after your last dose. Tell your healthcare professional right away if you become pregnant or think you are pregnant during treatment with Rozlytrek. It is not known if Rozlytrek passes into breast milk. Do not breastfeed during treatment with Rozlytrek and for 14 days after the final dose. Male patients must use highly effective birth control if their partner can get pregnant while they are on Rozlytrek and for 3 months after their last dose. Rozlytrek can cause you to feel faint, dizzy, or tired, give you blurred vision, mental status changes, confusion, and hallucinations. Do not drive or operate machines until you feel well. Do not use Rozlytrek if you are allergic to any ingredients in this drug or the bottle.

Before you start taking this medication, talk to your doctor about your medical history especially if you have:

• Bone fractures;
• Excess uric acid in your blood;
• Liver or kidney problems;
• Nervous system or cognitive problems;
• Or ever had eye or vision problems;
• Or have had any heart problems such as congestive heart failure (your heart does not pump blood as well as it should); long QT syndrome (a heart rhythm condition);
• Problems like fainting or passing out

Tell your doctor about all the medications you take including prescription, OTC, herbal supplements, and vitamins. The following may interact with Rozlytrek:

• Grapefruit and grapefruit juice;
• Itraconazole, ketoconazole, posaconazole and voriconazole (used to treat fungal and bacterial infections);
• Phenytoin, carbamazepine, phenobarbital (used to treat seizures);
• Rifampin, rifabutin (used to treat lung disease);
• Ritonavir, saquinavir (used to treat AIDS/HIV infection);
• St. John’s Wort (hypericum perforatum) (a herbal medicine, used to treat depression);
• Telithromycin (used to treat certain types of bacterial infection)

Questions and Answers

Why is Rozlytrek more affordable from Canada than the United States?

In general, all drug prices, not only Rozlytrek, are more affordable to order from Canada because the price of both the brand and generic medication is regulated by the government. Also, since we established in 2006, our vision is to provide safe and affordable medication to people in the US.

Is it safe to buy Rozlytrek from your pharmacy?

Our products are sourced only from facilities certified by authorities in the countries we import them from. CanadaPharmacyOnline.com has a rigorous process for selecting our partners, so that you, our customer, get the safest medicine. We are also a Certified Canadian Pharmacy that adheres to the requirements imposed by the Province of British Columbia.

What is the lowest price of Rozlytrek 200 mg per capsule?

Brand Rozlytrek 200 mg starts at $11,999.99 for 90 capsules, which is $133.33 per capsule.

How much is the shipping?

Our shipping fee is a flat rate of $10.00 per order. Our pharmacy focuses on getting you the lowest prices on high quality products.

How do I order from your pharmacy?

Ordering Rozlytrek from us is very simple. You can place the order online or call Customer Service at 1866.920.3784. For additional information or for the ordering process, visit our How to Order page.

Are your Rozlytrek prices competitive?

Yes, we are proud to offer some of the most competitive prices across Canadian pharmacies. In some cases, we might be able to either match or beat our competitors' prices. Please call our friendly customer service at 1866.920.3784.

Is there a limit on how many Rozlytrek tablets or capsules I am allowed to order at one time?

CanadaPharmacyOnline.com can only dispense a maximum of a three month supply of Rozlytrek at one time, as per your doctor's prescription.

Can I buy Rozlytrek over the counter from you?

No, Rozlytrek requires a valid prescription from your doctor. We do not sell this product without a valid prescription.

Do you ship to the United States?

Yes, we do. It usually takes between 7 and 18 business days to receive your order from our pharmacy.

Is there a generic for Rozlytrek?

No, there is no generic alternative for this product.

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The information on this page is sourced from independent third parties contracted by CanadaPharmacyOnline. While we cannot guarantee its medical accuracy, we strongly recommend consulting a healthcare professional for personalized advice regarding medications or medical conditions. Prices listed are in US dollars.

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Prescriptions Dispensed from Canada are Dispensed by Candrug Pharmacy #18985. 202A 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9, 604-543-8711. Pharmacy Manager: Carol Hou.
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